Synthesis, characterization, and antimicrobial activity of a new pyrimidine Schiff base and its Cu(II), Ni(II), Co(II), Pt(II), and Pd(II) complexes

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dc.contributor.authorGülcan, Mehmet
dc.contributor.authorSönmez, Mehmet
dc.contributor.authorBerber, İsmet
dc.date.accessioned2014-08-15T06:33:09Z
dc.date.available2014-08-15T06:33:09Z
dc.date.issued2012
dc.description.abstractA new Schiff base, {1-[(5-bromo-2-hydroxy-benzylidene)- amino]-4-phenyl-2-thioxo-1,2-dihyro-pyrimidin-5-yl}-phenyl-methanone, was synthesized from N-amino pyrimidine-2-thione and 5-bromsalicylaldehyde. Metal complexes of the Schiff base were prepared from acetate salts of Cu(II), Ni(II), Co(II), Pd(II), and PtCl2 in methanol. The chemical structures of the Schiff base ligand and its metal complexes were confirmed by spectroscopic analysis. All of the compounds were evaluated for their antimicrobial against 4 gram-positive bacteria, 1 gram-negative bacterium, and 3 yeast strains. The Schiff base and the Cu(II) and Co(II) complexes showed good biological activity against all tested bacteria and yeast strains.
dc.identifier.citationGülcan, M., Sönmez, M., Berber, İ. "Synthesis, characterization, and antimicrobial activity of a new pyrimidine Schiff base and its Cu(II), Ni(II), Co(II), Pt(II), and Pd(II) complexes". Turkish Journal of Chemistry, 36, (2012), 189-200.
dc.identifier.doi10.3906/kim-1104-2
dc.identifier.issn1300-0527
dc.identifier.issn1303-6130 (E-ISSN)
dc.identifier.scopus2-s2.0-84855247127
dc.identifier.scopusqualityQ3
dc.identifier.trdizinid123047
dc.identifier.urihttp://journals.tubitak.gov.tr/chem/issues/kim-12-36-1/kim-36-1-15-1104-2.pdf
dc.identifier.urihttps://hdl.handle.net/11486/335
dc.identifier.urihttps://doi.org/10.3906/kim-1104-2
dc.identifier.wosWOS:000300209600015
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkish Journal of Chemistry
dc.relation.publicationcategoryMakale - Kategorisiz
dc.subjectN-aminopyrimidine-2-thione
dc.subject5-bromosalicylaldehyde Schiff base
dc.subjectMetal complexes
dc.subjectAntimicrobial activity
dc.titleSynthesis, characterization, and antimicrobial activity of a new pyrimidine Schiff base and its Cu(II), Ni(II), Co(II), Pt(II), and Pd(II) complexes
dc.typeArticle

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