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  • Öğe
    Determination of earthquake resistance of historical masonry inn with finite element analysis
    (Springer, 2025)
    The protection of historic masonry structures against earthquakes is only possible by accurately assessing their non-linear behaviour, in particular their potential for severe damage and collapse. Experimental investigations on historic structures can be damaging, time consuming and costly. Therefore, in recent years, numerical modelling and analysis techniques have become common and reliable methods for determining the structural behaviour of historic structures. Turkey, which is located in a seismic zone, is home to many historical and cultural heritage sites. This study investigates the seismic performance of the historic Durak Han, located in the Dura & gbreve;an district of Sinop province due to its proximity to the North Anatolian Fault Line. The inn has been heavily damaged due to careless use and earthquakes and has been repaired many times. The seismic behaviour, force-displacement capacity and collapse mechanism of the stone vaulting have been investigated. A numerical simulation method had never been applied to the inn before. A comprehensive finite element model was constructed based on the architectural survey projects of the inn and this model was corrected using the experimental modal analysis results available in the literature. In order to determine the seismic behaviour and collapse mechanisms of the inn, nonlinear dynamic analyses were performed using the ground motion records of the 2023 Kahramanmara & scedil; earthquakes. The maximum principal stresses, maximum displacements and damage distributions of the inn were evaluated.
  • Öğe
    The Distinguishing Factor in Soccer Players is Aerobic Performance, not the ACTN3 Gene
    (Soc Chilena Anatomia, 2023) Zileli, Raif; Soyler, Mehmet; Diker, Gurkan; Ozkamci, Huseyin; Bayrakdaroglu, Serdar; Sever, Mehmet Onur; Can, Ibrahim
    The purpose of this study was to reveal the differences between ACTN3 genotype (RR, RX, XX) and aerobic performance [Yo-Yo IRT1 (m), VO2 max (ml/kg/min)] in professional and regional amateur league soccer players and to reveal which of these parameters was a distinctive factor in these athletes.71 professional soccer players (age: 23.66 +/- 4.11 years; body height: 1.79 +/- 6.99 m; body weight: 76.02 +/- 6.76 kg; body fat: 11.59 +/- 3.11 %) and 62 regional amateur soccer players (age: 23.63 +/- 3.77 years; body height: 1.81 +/- 5.77 m; body weight: 76.36 +/- 7.53 kg; body fat: 15.60 +/- 4.65 %) volunteered for the study. After DNA extraction from buccal epithelial cells via a commercial kit was performed for the genetic background of the athletes, Real-Time PCR was carried out for genotyping. Furthermore, Yo-Yo IRT1 test was performed to determine the aerobic performance of the soccer players. SPSS 23 (SPSS Inc., Chicago, IL, USA) package program was used for the statistical analysis of the data obtained in the tests. Shapiro-Wilk test for normality and Levene's test for homogeneity of variance were performed. Chi-Square, Independent Sample T Test and One Way ANOVA test were used in the analysis of the parameters. Statistical significance was set as p<0.05. In the study, there found no meaningful statistical significance in terms of the rs1815739 polymorphism in the ACTN3 gene between the groups (p>0.05); however, there was a statistical significance in favor of professional soccer players in terms of aerobic parameters (p<0.05). Consequently, it can be said that aerobic performance is the distinguishing factor, not the ACTN3 gene, in soccer players.
  • Öğe
    The effect of thrombosis-related laboratory values on mortality in COVID-19 infection
    (Verduci Publisher, 2023) Ergenc, Z.; Ergenc, H.; Ozturk, A.; Kaya, T.; Nalbant, A.; Karacaer, C.; Gunay, S.
    OBJECTIVE: COVID-19 may cause thrombosis in both venous and arterial systems. Familiarity with the signs and symp-toms of thrombosis and its treatment is essen-tial in treating COVID-19 infection and its com-plications. D-Dimer and mean platelet volume (MPV) are measurements related to the devel-opment of thrombosis. This study investigates whether MPV and D-Dimer values could be used to determine the risk of thrombosis and mortali-ty in the COVID-19 early stages.PATIENTS AND METHODS: 424 patients who were COVID-19 positive, according to the World Health Organization (WHO) guidelines, were randomly and retrospectively included in the study. Demographic and clinical character-istics such as age, gender, and length of hospi-talization were obtained from the digital records of participants. Participants were divided into living and deceased groups. The patients' bio-chemical, hormonal, and hematological param-eters were analyzed retrospectively.RESULTS: White blood cells (WBC), neutro-phils, and monocytes were significantly differ-ent in the two groups (p-value <0.001), and their values were lower in the living group than in the deceased group. MPV median values did not dif-fer according to prognosis (p-value = 0.994). While the median value was 9.9 in the survivors, it was 10 in the deceased. Creatinine, procalci-tonin, ferritin, and the number of hospitalization days in living patients were significantly lower than in patients who died (p-value <0.001). Me-dian values of D-dimer (mg/L) differ according to prognosis (p-value <0.001). While the median value was 0.63 in the survivors, it was found as 438 in the deceased.CONCLUSIONS: Our results did not show any significant relationship between the mortality of COVID-19 patients and their MPV levels. How-ever, a significant association between D-Di-mer and mortality in COVID-19 patients was ob-served.
  • Öğe
    Sprint and Anaerobic Power with the Soccer-Specific ACTN3 Gene: A Distintive Example
    (Soc Chilena Anatomia, 2024) Soyler, Mehmet; Zileli, Raif; Ozkamci, Huseyin; Diker, Gurkan; Sever, Mehmet Onur; Bayrakdaroglu, Serdar; On, Sadi
    The aim of this study is twofold: (1) to identify differences in certain anaerobic parameters (10m sprint, 30m sprint, anaerobic power, and Illinois agility tests) between professional and amateur soccer players, and (2) to determine whether there is a difference in the ACTN3 gene polymorphism between professional and amateur soccer players. Ultimately, the goal is to reveal which parameters contribute to the differentiation in these two aspects. A total of 133 volunteer soccer players, including 71 professionals and 62 amateurs, participated in the research. DNA extraction from buccal epithelial cells was performed using a commercial kit to determine the genetic background of the athletes, and Real -Time PCR was conducted for genotyping. Statistical analysis of the findings obtained from the test results was performed using the SPSS 23 (SPSS Inc., Chicago, IL, USA) package program. The homogeneity of variance of the data was assessed using the Levene Test, and normal distribution analyses were conducted using the Shapiro -Wilk Test. Chi-square and Mann -Whitney U tests were employed for parameter analysis. The significance level was set at p<0.05. Evaluation of the data in our study revealed no statistically significant difference in ACTN3 rs1815739 gene polymorphism between the groups (p>0.05). However, there is a statistically significant difference in anaerobic parameters (10m sprint, 30m sprint, and anaerobic power) except for the Illinois test (p<0.05). In conclusion, our study found that gene polymorphism is not a differentiating factor between professional and amateur soccer players, but speed (10m and 30m) and anaerobic power parameters are differentiating factors.
  • Öğe
    A CASE STUDY: ECOLOGICAL QUALITY STATUS OF SUSURLUK RIVER BASIN (MARMARA SEA)
    (Parlar Scientific Publications (P S P), 2019) Albayrak, Serhat; Caglar, Senem; Mulayim, Aysegul; Kurt-Sahin, Guley; Balkis, Husamettin; Cinar, Nur Findik; Atabay, Hakan
    This study was carried out with the aim of determining the Ecological Quality Status (EQS) of coastal transitional waters of Susurluk River Basin (Marmara Sea). Macrozoobenthic invertebrate material was collected in May of 2013 from six stations in triplicate by means of a van Veen grab. Shannon-Weaver Diversity Index and associated Pielou's Evenness Index together with biotic indices AMBI and BENTIX were calculated. Some ecological variables (Secchi disc depth, temperature, salinity, dissolved oxygen, pH, total phosphorus, total nitrogen, silica, Chlorophyll-a) of the sea water and total organic carbon of the sediment were also measured. Ecological Quality Status at each station was assessed by considering individual dominancy of sensitive and tolerant species, results from univariate/biotic indexes and some ecological parameters. When EQS of the basin is evaluated as a whole, it was seen that there was not any station in Good or High EQS at the study area, stations were in Poor or Bad EQS at the stations where the River meets the sea, while the stations off the River mouth were in Moderate EQS. Both species pattern of macrozoobenthic invertebrate communities and ecological parameters determined in the basin such as TOC and nutrients present the negative impacts of the River over the basin and indicate the necessity of efficient precautions to be taken.
  • Öğe
    THE EFFECT OF DIMETHOATE ON CAPOETA CAPOETA (GULDENSTAEDT 1773) AND THE PROTECTIVE EFFECT OF ASCORBIC ACID
    (Parlar Scientific Publications (P S P), 2016) Tanriverdi, Erdi Anil; Yilmaz, Muhitdin; Koc, Evren; Akgul, Ali; Ersan, Yusuf
    In this study, Dimethoate (DM) (a pesticide)'s histopathological and electrophoretic effects were investigated on Capoeta capoeta (Guldenstaedt 1773) that were captured from Kars creek, and the protective effect of ascorbic acid (AA) (vitamin C) was tested. After allowing time for their adaptations to their new environment, the fish caught from Kars creek were divided into 4 groups (each including 10 fish), and placed in 300-liter tanks in the laboratory. The fish were kept in water containing different solutions: group I in normal water medium, group II in 100 mg/L AA, group III in 2 mg/L DM, and group IV in 100 mg/L AA and 2 mg/L DM. They were kept in these water mediums for 10 days. After this period, blood and tissue samples were taken from the fish for electrophoretic and histopathological studies. Tissue samples were detected in 10% formaldehyde solution and paraffin blocks were prepared by routine histological methods. The samples were cut into sections 3-5 thick, all stained according to hematoxylin and eosin staining methods, and they were examined under a microscope. Obtained serum samples were carried out in Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE). When we compared the serum samples with the control group of fish, protein bands in the application of 100 mg/L AA and 2 mg/L DM, thickening in 36 kD band, thinning in 100 kD, 97 kD, 76 kD, 56 kD and 30 kD bands were observed, and the bands of 93 kD, 46 kD, 44 kD and 26 kD were detected as newly-synthesized in SDS-PAGE electropherogram. In the histopathological examinations, depending on DM in intestine, liver, and kidney tissues obtained from the group formed by application of DM and AA, degeneration, necrosis, pyknotic nuclei and cell infiltrates were detected. As a result, whereas DM application was found to create toxic effects on Capoeta capoeta, AA was found to have a healing effect.
  • Öğe
    Impact of traumatic rib fractures on pulmonary morbidity and mortality: A multicenter prospective study
    (European Respiratory Soc Journals Ltd, 2013) Citak, Necati; Pekcolaklar, Atilla; Kok, Abdulaziz; Denizkiran, Ibrahim; Geyik, F. Dogu; Oz, I. Ilker; Evman, Serdar
    [No abstract available]
  • Öğe
    EFFECTS OF GLYPHOSATE (HERBICIDE) ON SERUM PARAOXONASE ACTIVITY, HIGH DENSITY LIPOPROTEIN, TOTAL ANTIOXIDANT AND OXIDANT LEVELS IN KARS CREEK TRANSCAUCASIAN BARBS (CAPOETA CAPOETA [GULDENSTAEDT, 1773])
    (Parlar Scientific Publications (P S P), 2017) Deveci, Haci Ahmet; Unal, Sevgi; Karapehlivan, Mahmut; Ayata, Muradiye Karasu; Gaffaroglu, Muhammet; Kaya, Inan; Yilmaz, Muhitdin
    The aim of this study is to explore the effects of the herbicide glyphosate on serum paraoxonase (PON1) activity, high-density lipoprotein (HDL), and total antioxidant (TAS) and oxidant (TOS) levels in Kars Creek Transcaucasian Barbs (Capoeta capoeta [Guldenstaedt, 1773]). Twenty four Capoeta capoeta are chosen within a weight range of 200 to 240 grams and they are equally divided into 3 groups, namely Groups I, II, III. The fish placed in Group I are received aquatic environment while Groups II and III were kept in aquatic environments with a pH value of 7.4 in tanks to which 0,01 and 0,02 mg/L glyphosate (N-phosphonomethyl glycine 480 mg/L), respectively. It was found that groups II and III had significantly lower serum plasma PON1, HDL and TAS levels than the control group (Group I). On the other hand, serum TOS levels were found significantly elevated in Groups II and III, in comparison to the control group. In this work, significant changes were found in the serum paraoxonase activity, HDL, TAS and TOS levels of fishes living in environments added 0.01 and 0.02 mg/L glyphosate.
  • Öğe
    Voltammetric Determination of Hydroxylamine Using a Ferrocene Derivative and NiO/CNTs Nanocomposite Modified Carbon Paste Electrode
    (Esg, 2015) Golestanifar, Fereshteh; Karimi-Maleh, Hassan; Atar, Necip; Aydogdu, Ercan; Ertan, Bengu; Taghavi, Mehdi; Yola, Mehmet Lutfi
    The electrochemical activities of hydroxylamine (HX) as a pollutant compound at a 1,1-bis(phenylacetyl) ferrocenele/NiO/CNTs modified carbon paste electrode (1,1-BPF/NiO/CNTs/CPE) has been studied. 1,1-BPF was used as a suitable mediator for elecrocatalytic interaction with HX. The voltammetric properties of HX at the 1,1-BPF/NiO/CNTs/CPE was investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry, and square wave voltammetry (SWV) methods. The oxidation peak current increases linearly with HX concentration in the range 0.5-250.0 mu M and the detection limit for HX was 0.2 mu M. The sensor was applied to wastewater samples with excellent performance.
  • Öğe
    Plantago major Protective Effects on Antioxidant Status after Administration of 7,12-Dimethylbenz(a)anthracene in Rats
    (Asian Pacific Organization Cancer Prevention, 2011) Oto, Gokhan; Ekin, Suat; Ozdemir, Hulya; Demir, Halit; Yasar, Semih; Levent, Abdulkadir; Berber, Ismet
    Aim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase (P<0.05), carbonic anhydrase (p <= 0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) values was observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage in Wistar albino rats that might be due to decreased free radical generation.
  • Öğe
    Doppler ultrasonographic findings in cases with Hashimoto thyroiditis
    (Kuwait Medical Assoc, 2020) Gokosmanoglu, Feyzi; Aksoy, Erkan; Onmez, Attila; Ergenc, Hasan
    Objective: To investigate the effect of thyroid-stimulating hormone (TSH) levels on hemodynamic indexes in color doppler ultrasonography in patients with Hashimoto's disease Design: Prospective observational study Setting: Departmant of Endocrinology, Medical Park Hospital, Ordu, Turkey Subjects: One hundred and twelve patients Intervention: The patients were divided into two groups: Group 1, TSH: 0.35-4.94 mIU/L; and Group 2, TSH >4.94 mIU/L. The mean peak systolic velocity (mPSV), mean end diastolic velocity (EDV) and mean resistive index (RI) of the inferior thyroid artery were measured using doppler ultrasonography at the appropriate angle (45-60 degrees C). Main outcome measure: The mPSV, EDV and RI of the inferior thyroid artery Results: A total of 48.21% of the patients (n=54) were in Group 1 and 51.78% of them (n=58) were in Group 2. In our study, we found that as the TSH levels increased, the thyroid blood flow and RI decreased in patients with Hashimoto's disease and with clinical and subclinical hypothyroidism compared with normal ones. Conclusion: The TSH level in Hashimoto's disease and the vascular RI increases as the parenchymal damage increases.
  • Öğe
    CAILLOU: A CARTOON ALL CHILDREN ADMIRE
    (Iated-Int Assoc Technology Education A& Development, 2011) Akman, B.; Yagan, S.; Ozer, G.; Kaya, A.; Zorlu, G.; Sahillioglu, D. Erol
    The advent of technology, reduction of playgrounds and parents` intensive working hours has led children watch television. Cartoons are known to be the most watched program while children watching television. The development and expansion of the cartoons industry resulted in cartoon characters to be well-known and accepted in the variety of society. In this context, the basic reason for this study is to determine the reasons of the Caillou, which followed by many children in recent times and well-known in various sectors in Turkey, is preferred by children. For this purpose, the data were collected in the range of 36-72 months of 126 children in the province of Zonguldak, Sinop and Ankara during the 2010-2011 academic year's spring semester. The data were collected through semi-structured interview generated by researches and pictures of children. The researchers primarily wanted from children to draw their favorite cartoon character and then tell something about the drawing. Subsequently, researchers conducted semi-structured interviews with children. Survey method was used for the study and the data interpreted via descriptive analysis technique. According to the findings of the study why children specified that they like Calliou the most because of his games and his toys and the most unpopular feature of his wrongdoing behaviour form time to time. Children, who participate the survey, answered for the question of which character they want to be; the girls said that Caillou's sister Rozi and the boys stated that they wanted to be Caillou. This finding of the research may be explained that children indentify the main hero of the cartoon with their sex.
  • Öğe
    DOES BOSU TRAINING AFFECT ON DYNAMIC AND STATIC BALANCE IN ADOLESCENT TAEKWONDO ATHLETES?
    (Univ Ljubljana, Fac Sport, 2018) Ipekoglu, Gokhan; Karabiyik, Hakan; Er, Fatmanur; Erdogan, Ceren Suveren; Cakir, Ergun; Koz, Mitat; Baltaci, Gul
    The purposes of this study were to develop taekwondos-pecific core stabilization-balance training and to determine the influence of a core stabilization-exercise protocol, using the BOSU, on dynamic and static balance performance in adolescent TKD athletes. Twenty-four elite taekwondo athletes were randomly divided into two groups: the BOSU-trained group (n = 13) and the control group (n = 11). Subjects in BOSU-trained group had core-stabilization training 3 times a week for 12 weeks in addition to the routine taekwondo training program. The control group had no training protocol in addition to the routine taekwondo training program. Static and dynamic balances of the subjects, both right and left legs were assessed with the Biodex Balance System. ANOVAs showed that the BOSU decreased both the static and the dynamic balance error scores of non-dominant leg from pre to post-training by 0.32 +/- 0.17 (28.5%) and 0.75 +/- 0.47 (82.5%); respectively (p<0.05). Furthermore, the BOSU decreased the dynamic balance error scores of dominant leg from pre to post-training by 40.33% (p<0.05). This study demonstrates that the taekwondo-specific BOSU training program is effective in decreasing the balance error scores in dominant and non-dominant leg. It is suggested that the BOSU training can be applied as an effective exercise program for enhancing dynamic and static balance performance.
  • Öğe
    Electrophysiological and histopathological effects of mesenchymal stem cells in treatment of experimental rat model of sciatic nerve injury
    (E-Century Publishing Corp, 2015) Yarar, Ercan; Kuruoglu, Enis; Kocabicak, Ersoy; Altun, Adnan; Genc, Eyup; Ozyurek, Hamit; Kefeli, Mehmet
    Aim: The aim of this study was to evaluate electrophysiological and histopathological effects of mesenchymal stem cells in treatment of sciatic nerve injury. Material and methods: Thirty-two female Spraque-Dawley rat were used in this study. Eight rats were used as a reference group in electrophysiological analysis for evaluation of non-injured nerve recordings (Control Group). Twenty-four rats were used for experimental evaluation. Twelve rats were anastomosed without treatment with mesenchymal stem cells (Sham Group) and twelve other rats were anastomosed and treated with mesenchymal stem cells (Stem Cell Group). Surgicel and bioglue were used in anastomosed line in both Groups. Eight weeks after the surgery, electrophysiological evaluation of rats was performed and, then, rats were decapitated under anesthesia and specimens including sciatic nerves and anastomosed line were taken for histopathological evaluation. Electromyography and nerve conduction velocity testing and histopathological scoring including rate of Wallerian degeneration, and neuroma and scar formation were evaluated for both Groups. Results: There were no statistically significant differences between Sham and Stem Cell Groups with respect to histopathological evaluation. However, nerve conduction velocity showed significant difference between groups (P = 0.001). Nerve conduction velocity was significantly improved in Stem Cell Group when compared to Sham Group. Conclusion: In this study, based on nerve conduction velocity data, it was concluded that treatment with mesenchymal stem cells during end-to-end anastomosis improves functional regeneration.
  • Öğe
    Prevention of recurrent cryptogenic stroke with percutaneous closure of patent foramen ovale; a follow-up study with magnetic resonance imaging
    (Oxford Univ Press, 2013) Sunman, H.; Ates, A.; Yorgun, H.; Canpolat, U.; Sahiner, L.; Kaya, B.; Aytemir, K.
    [No abstract available]
  • Öğe
    Cumulus cells and follicular fluid show alterations in bone morphogenic protein 15 (BMP-15), growth differentiation factor 9 (GDF-9), and oxidative status in patients with endometriosis
    (Oxford Univ Press, 2019) Ruso, H.; Dayanir, D.; Kalem, Z.; Tural, R.; Saribas, S.; Dincel, A. Sepici; Ozogul, C.
    [No abstract available]
  • Öğe
    Effect of Timokinon and 7-Nitroindazol Combination on Penicilin Induced Epileptiform Activity in Rat
    (Wiley-Blackwell, 2015) Altinkaynak, Elif; Arslan, Gokhan; Alici, Sabiha Kubra; Ayyildiz, Mustafa; Agar, Erdal
    [No abstract available]
  • Öğe
    Finite element analysis of stress distribution of 2 different tooth preparation designs in porcelain-fused-to-metal crowns
    (Quintessence Publishing Co Inc, 2006) Oyar, P; Ulusoy, M; Eskitascioglu, G
    Purpose: The aim of this clinical simulation study was to investigate the effect of anatomic and nonanatomic occlusal preparation design on stress distribution in different metal-ceramic crowns and tooth and bone. Materials and Methods: For the finite element analysis method, a 2-dimensional mathematical model of a mandibular second premolar tooth and its supporting tissues was used. The analysis was performed by using a structural analysis program. Four groups were designed: gold-palladium alloy/anatomic occlusal preparation (Au-Pd/A), Au-Pd alloy/nonanatomic (flat) occlusal preparation (Au-Pd/N), nickel-chromium alloy/anatomic occlusal preparation (Ni-Cr/A), and Ni-Cr alloy/nonanatomic occlusal preparation (Ni-Cr/N). A distributed type load of 400 N (total) was applied to the centric stop points on the tip of the buccal cusp and on the central developmental groove in centric occlusion to all types of restorations. Results: The results demonstrated that shear stresses in the dentin tissues and restorations in Au-Pd/A and Ni-Cr/A were similar. The shear stresses within the restorations in Au-Pd/N and Ni-Cr/N were similar. Conclusion: Anatomic occlusal preparation designs were advantageous in stress distribution in the dentin tissue. Nonanatomic occlusal preparation designs were found to be advantageous in the stress amount and distribution in the porcelain structure. Occlusal preparation designs and restorative materials showed no differences in stress distribution and amount in the pulp tissue and bone tissues.
  • Öğe
    Method Validation and Simultaneous Determination of Retinol, Retinyl Palmitate, β-Carotene, α-Tocopherol and Vitamin C in Rat Serum Treated with 7,12 Dimethylbenz[a]Anthracene and Plantago major L. by High-Performance Liquid Chromatography Using Diode-Array Detection
    (Bentham Science Publ Ltd, 2013) Levent, Abdulkadi; Oto, Gokhan; Ekin, Suat; Berber, Ismet
    A new and simple high-performance liquid chromatography method was developed and validated for the simultaneous determination of retinol, retinyl palmitate, beta-carotene, alpha-tocopherol and vitamin C in rat serum treated with Plantago Major L. and 7,12 dimethylbenz[a] anthracene. High-performance liquid chromatography analysis was performed utilizing an Inertsil ODS3 reversed phase column with methanol-tetrahydrofuran-water as mobile phase under gradient conditions, at 1.5 mL min(-1) flow rate and 25 degrees C. Diode-array detection was at 325, 450, 290 and 270 nm (retinol and retinyl palmitate), beta-carotene, alpha-tocopherol and vitamin C, respectively and runnig time 18 min. The high-performance liquid chromatography assay and extraction procedure proposed are simple, rapid, sensitive and accurate. The method was then applied for the determination of retinol, retinyl palmitate, beta-carotene, alpha-tocopherol and vitamin C in rat serum. Results of this study demonstrated that; at 60th day DMBA-treated group, there was a significant decrease in vitamin levels compared to the levels of control group. A significant increase was observed in vitamin levels of 7,12 dimethylbenz[a]anthracene+Plantago Major L.-treated group compared to the DMBA-treated group. Additionally, the results obtained in the study are found to be in agreement with data reported in the literature.
  • Öğe
    Facile Synthesis and Crystal Structures of New Ammonium Sulfonates (CA-DNBS and TEA-TMBS)
    (Chinese Journal Structural Chemistry, 2013) Khan, Islam Ullah; Arshad, Muhammad Nadeem; Sahin, Onur; Mubashar-Ur-Rehman, Hafiz; Munir, Ayesha; Humayun, Saba; Asiri, Abdullah M.
    The title compounds, C12H10N3O7SCl (I) and C15H27NO3S (II), crystallize in the monoclinic system, space group P2(1)/c with a = 7.3995(1), b = 27.8489(6), c = 9.8246(2) angstrom, beta = 131.349(1)degrees, V = 1519.82(5) angstrom(3), Z = 4, F(000) = 768, R-int = 0.033 and S = 1.03 for I, and in the orthorhombic system, space group Pbca with a = 8.6227(1), b = 16.1480(4), c = 23.8774(6) angstrom, V = 3324.67(12) angstrom(3), Z = 8, F(000) = 1312, R-int = 0.024 and S = 1.04 for II. We have devised a convenient procedure for the synthesis of fused organic salts resulting from 1:1 proton-transfer, using an amine and a derivative of benzenesulfonic acid. The synthesized salts have a number of applications ranging from their consumption as eco-friendly solvents and catalysts in organic syntheses, to being used as efficient precursors for the production of sulfa drugs. Structures of compounds 3-chloroanilinium 2,4-dinitrobenzenesulfonate (CA-DNBS) and triethylaminium 2,4,6-trimethylbenzenesulfonate (TEA-TMBS) were determined by single-crystal X-ray diffraction studies and infrared spectroscopy.