Sinop Üniversitesi Kurumsal Akademik Arşivi
DSpace@Sinop, Sinop Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Protective effect of Asphodelus aestivus Brot. on bladder injury due to ischemia-reperfusion: Biochemical and histopathological Study
(Natl Inst Science Communication-Niscair, 2025) Kopar, Hatice; Yagmur, Isil; Kurutas, Ergul Belge; Tural, Rabia
Severe oxidative stress caused by reperfusion after ischemia in the bladder causes serious functional and structural damage. New molecules with antioxidant effects are needed to protect against this damage. In our study, we aimed to investigate the effect of Asphodelus aestivus on the oxidant-antioxidant system in bladder ischemia/reperfusion (I/R) injury induced in rats biochemically and histopathologically. In our study, 24 three-month-old male Wistar-Albino rats weighing 250-300 g were randomly divided into 3 groups of 8 rats each: sham group (I/R+serum physiological, 1mL) (group 1), I/R group (group 2), I/R+A. aestivus group (50 mg/kg/day) (treatment group, group 3). At the end of the experiment, all rats were sacrificed and their bladder tissues were taken and divided into 2 parts for biochemical and histopathological examination. Protein amount, malondialdehyde (MDA) levels and superoxide dismutase (SOD) and catalase (CAT) enzyme activity levels were measured spectrophotometrically, and histopathological examination was performed under a light microscope. MDA levels were significantly higher and CAT activity was significantly lower in the I/R group compared to the sham and treatment groups (P<0.05). In histopathological examination, it was determined that there was a significant regression and/or decrease in the findings caused by I/R injury in the group treated with A. aestivus. A. aestivus has a protective effect in reducing oxidative stress in bladder I/R injury.
On Direct Estimates and Approximation Results by the Kantorovich Operators in Weighted Grand Lebesgue Spaces
(Padova Univ Press, 2026) Aydin, Ismail; Akgun, Ramazan
We give some new embeddings results for weighted grand Lebesgue spaces L-omega(p)),delta (Omega), where Omega subset of R-d is a open bounded subset. We also obtain the boundedness of the Kantorovich operator K-n in L-omega(p),delta) [0, 1]. In addition, we establish two direct estimates by K-functionals of the rate of approximation in L-omega(p),delta) [0,1].We generalize the direct estimate inequality in classical Lebesgue spaces L-p [0,1] to L-omega(p),delta)[0,1] using the boundedness of the Hardy-Littlewood maximal operator in L-omega(p),delta) [0,1]. Finally, we obtain similar results in [8] for the spaces L-omega(p),delta) [0,1].
Determination of Amylolytic and Proteolytic Enzyme Activity Characteristics of Thermophilic Actinobacteria Isolated from Amasya-Terziköy Thermal Spring
(Istanbul Univ Press, Fac Aquatic Sciences, 2025) Tatar, Demet; Veysioglu, Aysel; Tokatli, Ali; Duyar, Hunkar Avni
Actinobacteria represent a group of Gram-positive microorganisms characterized by high G+C content and are commonly found in both terrestrial and aquatic ecosystems. These bacteria are notable for their capacity to synthesize a wide range of bioactive compounds, including antibiotics and industrial enzymes. Their ability to withstand extreme environmental conditions allows them to colonize challenging habitats, such as thermal springs. These geothermal environments are critical not only for harboring microbial diversity but also for the discovery of novel bioactive substances with therapeutic potential. This study focused on isolating thermophilic actinobacteria from Terzik & ouml;y Thermal Spring in Amasya, T & uuml;rkiye, followed by phylogenetic analysis through 16S rRNA gene sequencing. The enzymatic capacities of the isolates-specifically amylase and protease production-were also assessed. Fourteen of the 21 isolates underwent 16S rRNA sequencing, resulting in the identification of eight Streptomyces, four Nocardia, one Actinomadura, and one Pseudonocardia species. Among these, seven isolates demonstrated amylase activity, and one displayed protease production. Notably, one Streptomyces isolate exhibited both enzymatic activities. These results highlightthe phylogenetic diversity ofthermophilic actinobacteria in geothermal environments and their potential as sources of thermostable enzymes for industrial applications.
SURVEILLANCE OR SUPPORT? A SYSTEMATIC LITERATURE REVIEW OF ARTIFICIAL INTELLIGENCE SUPPORTED PROCTORED ONLINE EXAMS
(Anadolu Univ, 2026) Ustun, Aysin Gaye; Kayali, Bunyami; Yavuz, Mehmet; Bozkurt, Aras
Proctored online exams have become widespread, especially after COVID-19, increasing exam security and efficiency. In recent years, artificial intelligence developments have increased these systems' importance by expanding their use. Accordingly, this study aims to provide an in-depth understanding of the conceptual structure of artificial intelligence-supported proctored online examination (AI-SPOE) research. Systematic literature review and text mining were used as methods. Thirty-two studies in Scopus and Web of Science databases were analyzed according to the PRISMA technique. While all the studies were examined in the context of content analysis, abstracts and keywords of the relevant studies were analyzed by text mining. The current study found it effective in increasing academic integrity and exam security, but problems such as privacy violations, exam anxiety, and algorithmic biases were encountered. Although methods such as biometric verification and behaviour analysis successfully detect cheating, technical difficulties, and false positives negatively affect the user experience. In the future, more inclusive designs, transparent algorithms, and alternative evaluation methods are suggested. In conclusion, the study emphasizes the potential of AI-SPOE systems and highlights the importance of ethical and technical improvements.
Approximation Results on an Infinite Interval Based on Power Series Statistical Sense
(Padova Univ Press, 2025) Yildiz, Sevda; Demirci, Kamil; Dirik, Fadime
This paper introduces a new approximation theorem, type of Korovkin, for positive linear operators (pLO) defined on the Banach space C-* [0, infinity) comprising all real-valued continuous functions on [0, infinity) that converge to a finite limit as their argument approaches infinity. By applying statistical convergence with respect to power series methods and employing the test functions 1, exp(-u) and exp(-2u), we derive a novel approximation result. Our findings demonstrate that the proposed method outperforms classical and statistical approaches, as illustrated by a concrete example. Furthermore, we explore the rate of convergence associated with this new approximation theorem.
