Synthesis, Spectroscopic Characterization, Single-Crystal Structure, Hirshfeld Surface Analysis, and Antimicrobial Studies of 3-Acetoxy-2-methylbenzoic Anhydride

Basit Öğe Kaydı
dc.authoridVeyisoglu, Aysel/0000-0002-1406-5513
dc.authoridCAKMAK, Sukriye/0000-0002-2221-0098
dc.authoridYAKAN, HASAN/0000-0002-4428-4696
dc.authoridAzam, Mohammad/0000-0002-4274-2796
dc.contributor.authorCakmak, Sukriye
dc.contributor.authorKansiz, Sevgi
dc.contributor.authorAzam, Mohammad
dc.contributor.authorVeyisoglu, Aysel
dc.contributor.authorYakan, Hasan
dc.contributor.authorMin, Kim
dc.date.accessioned2025-03-23T19:35:50Z
dc.date.available2025-03-23T19:35:50Z
dc.date.issued2022
dc.departmentSinop Üniversitesi
dc.description.abstractWe report a novel anhydride derivative, 3-acetoxy-2-methylbenzoic anhydride (AMA), obtained from the interaction of 3-acetoxy-2-methylbenzoyl chloride with 3-acetoxy-2-methylbenzoic acid. The synthesized compound was characterized by elemental analysis, IR, H-1 NMR, and C-13 NMR spectroscopic studies and single-crystal X-ray crystallography which revealed the crystallization of AMA as monoclinic with space group P2(1)/c. A Hirshfeld surface analysis was performed to record various intermolecular interactions, indicating the stabilization of the AMA structure by the intermolecular weak C-H center dot center dot center dot O hydrogen bonds and pi center dot center dot center dot pi interactions. The title compound was screened for antibacterial and antifungal activities using a serial dilution technique under aseptic conditions. The results indicate that the title compound has significant antibacterial properties but showed no antifungal behavior.
dc.description.sponsorshipKing Saud University, Riyadh, Saudi Arabia [RSP-2021/147]
dc.description.sponsorshipThe authors acknowledge the financial support through Researchers Supporting Project number (RSP-2021/147), King Saud University, Riyadh, Saudi Arabia.
dc.identifier.doi10.1021/acsomega.2c00879
dc.identifier.endpage17201
dc.identifier.issn2470-1343
dc.identifier.issue20
dc.identifier.pmid35647448
dc.identifier.scopus2-s2.0-85131147650
dc.identifier.scopusqualityQ1
dc.identifier.startpage17192
dc.identifier.urihttps://doi.org/10.1021/acsomega.2c00879
dc.identifier.urihttps://hdl.handle.net/11486/5946
dc.identifier.volume7
dc.identifier.wosWOS:000820291200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAmer Chemical Soc
dc.relation.ispartofAcs Omega
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250323
dc.subjectCarboxylic-Acid Anhydrides
dc.subjectIntermolecular Interactions
dc.subjectAldehydes
dc.subjectVisualization
dc.subjectEsters
dc.subjectCdc
dc.subjectDft
dc.titleSynthesis, Spectroscopic Characterization, Single-Crystal Structure, Hirshfeld Surface Analysis, and Antimicrobial Studies of 3-Acetoxy-2-methylbenzoic Anhydride
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu