The frequency of retrotransposon human endogenous retrovirus-K113 and a preliminary analysis of some microbial clues in bipolar disorder

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dc.authoridAvsar, cumhur/0000-0002-4095-0022
dc.contributor.authorYegin, Zeynep
dc.contributor.authorAvsar, Cumhur
dc.contributor.authorSarisoy, Gokhan
dc.date.accessioned2025-03-23T19:27:11Z
dc.date.available2025-03-23T19:27:11Z
dc.date.issued2020
dc.departmentSinop Üniversitesi
dc.description.abstractAim: The aim of our study was to investigate whether the retrotransposon human endogenous retrovirus (HERV)-K113 could be related with bipolar disorder or not. As a second and a preliminary aim, we also conducted bacterial screening in whole blood in a limited number of samples. Patients & methods: Three separate PCR reactions including the preintegration sites and sites within the viral sequences were performed for HERV-K113 detection. Bacterial screening was performed with SSCP/sequencing analysis. Results & conclusion: No difference was observed in terms of the frequency of retrotransposon HERV-K113 in Turkish bipolar disorder patients and healthy controls. SSCP/sequencing and alignment analysis for bacterial screening reflected the possible presence of different bacteria. We strongly recommend the broadened retrotransposon and microbial diversity analyses in bipolar disorder for future studies.
dc.identifier.doi10.2217/fmb-2020-0166
dc.identifier.issn1746-0913
dc.identifier.issn1746-0921
dc.identifier.issue17
dc.identifier.pmid33215524
dc.identifier.scopus2-s2.0-85097937780
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.2217/fmb-2020-0166
dc.identifier.urihttps://hdl.handle.net/11486/4862
dc.identifier.volume15
dc.identifier.wosWOS:000591192500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFuture Medicine Ltd
dc.relation.ispartofFuture Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectbipolar disorder
dc.subjectHERV-K113
dc.subjecthuman endogenous retrovirus
dc.subjectmicrobiota
dc.subjectretrotransposon
dc.titleThe frequency of retrotransposon human endogenous retrovirus-K113 and a preliminary analysis of some microbial clues in bipolar disorder
dc.typeArticle

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