Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine

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dc.authoridCELEBI, METIN/0000-0003-1475-8878
dc.contributor.authorSonmez, Mehmet
dc.contributor.authorCelebi, Metin
dc.contributor.authorBerber, Ismet
dc.date.accessioned2025-03-23T19:41:45Z
dc.date.available2025-03-23T19:41:45Z
dc.date.issued2010
dc.departmentSinop Üniversitesi
dc.description.abstractA phenol based novel Schiff base polydentate symmetric ligand was prepared. The complexes were prepared by reacting ligand and the metal chlorides of Cu (II), Ni(II), Co(II) and Fe(II) in methanol to get a series of mononuclear complexes. The complexes were characterized by elemental analyses, conductivity measurements, magnetic susceptibility data, IR, UV-Vis, NMR and API-ES mass spectral data. The mononuclear structure of the complexes was confirmed on the basis of elemental analyses, magnetic susceptibility and API-ES mass spectral data. The ligand and all the metal complexes were evaluated for their antimicrobial activity against four Gram-positive bacteria (Staphylococcus aureus ATCC 6538, S. aureus ATCC 25923, Bacillus cereus ATCC 7064 and Micrococcus luteus ATCC 9345), one Gram-negative bacterium (Escherichia coli ATCC 4230), and three yeast (Candida albicans ATCC 14053, Candida krusei ATCC 6258 and Candida parapsilosis ATCC 22019) strains. Therefore, newly synthesized the ligand and two complexes [(Cu(II) and Co(II)] showed good biological activity against all tested bacteria and yeast strains. (C) 2010 Elsevier Masson SAS. All rights reserved.
dc.description.sponsorshipUniversity Yuzuncu Yil [2007-FED-B41]
dc.description.sponsorshipWe are grateful to Presidency of Scientific Research Projects of University Yuzuncu Yil (2007-FED-B41) for the support of this research.
dc.identifier.doi10.1016/j.ejmech.2010.01.035
dc.identifier.endpage1940
dc.identifier.issn0223-5234
dc.identifier.issn1768-3254
dc.identifier.issue5
dc.identifier.pmid20163896
dc.identifier.scopus2-s2.0-77949491217
dc.identifier.scopusqualityQ1
dc.identifier.startpage1935
dc.identifier.urihttps://doi.org/10.1016/j.ejmech.2010.01.035
dc.identifier.urihttps://hdl.handle.net/11486/6636
dc.identifier.volume45
dc.identifier.wosWOS:000276695200030
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier France-Editions Scientifiques Medicales Elsevier
dc.relation.ispartofEuropean Journal of Medicinal Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectSymmetric Schiff base
dc.subjectMononuclear complexes
dc.subject2,6-Diformyl-4-methylphenol
dc.subjectN-aminopyrimidine
dc.subjectBiological activity
dc.titleSynthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine
dc.typeArticle

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