Environmental pollutant sodium omadine: toxic effects in zebra fish (Danio rerio)

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dc.authoridGUNAL, AYSEL CAGLAN/0000-0002-9072-543X
dc.contributor.authorYilmaz Sezer, Ilknur
dc.contributor.authorKocak, Gulsum
dc.contributor.authorTural, Rabia
dc.contributor.authorGenal, Aysel caglan
dc.contributor.authorSepici Dincel, Aylin
dc.date.accessioned2025-03-23T19:34:46Z
dc.date.available2025-03-23T19:34:46Z
dc.date.issued2024
dc.departmentSinop Üniversitesi
dc.description.abstractIn recent years one of the most striking results of over-population and consumption activities in the world is the rapid increase in environmental pollutants. Environmental pollutants, one of the harmful consequences of technological and modern life, threaten the health of people and other living organisms. In this study, we aimed to determine the effects of sodium omadine (NaOM) on superoxide dismutase enzyme (SOD) activity as an antioxidant and on 8-OHdG levels as oxidative DNA damage in zebrafish. Zebrafish, obtained from the aquarium fish producer, were stocked in experimental aquariums to ensure their adaptation period to the experimental conditions 15 days before the experiment. The fish were exposed to 1 ug/L and 5 ug/L concentrations of NaOM for 24, 72, and 96 h. SOD enzyme activity (U/100 mg tissue) and 8-OHdG (pg/100 mg tissue) were measured using commercial kits. The statistically significant differences in tissue SOD levels and data for DNA damage between the groups were determined as time and dose-dependent (p < 0.05). Biocidal products are environmental pollutants that cause changes in antioxidant enzyme activities, especially in non-target organisms. Marine pollution and the degradation of ecosystems directly affect people, and the results of the study offer awareness of health problems, environmental pollution, and marine pollution.
dc.description.sponsorshipThis study was supported by the Gazi University Scientific Project Unit with Project no: 01/2017-31. The authors would like to thank Sahra Setenay Baran for evaluating the data. [01/2017-31]; Gazi University Scientific Project Unit
dc.description.sponsorshipThis study was supported by the Gazi University Scientific Project Unit with Project no: 01/2017-31. The authors would like to thank Sahra Setenay Baran for evaluating the data.
dc.identifier.doi10.1080/15376516.2023.2279717
dc.identifier.endpage261
dc.identifier.issn1537-6516
dc.identifier.issn1537-6524
dc.identifier.issue3
dc.identifier.pmid37964616
dc.identifier.scopus2-s2.0-85176965768
dc.identifier.scopusqualityQ2
dc.identifier.startpage256
dc.identifier.urihttps://doi.org/10.1080/15376516.2023.2279717
dc.identifier.urihttps://hdl.handle.net/11486/5732
dc.identifier.volume34
dc.identifier.wosWOS:001105199400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofToxicology Mechanisms and Methods
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectEnvironmental pollutant
dc.subjectsuperoxide dismutase enzyme activity
dc.subjectDNA damage
dc.subjectsodium omadine
dc.subjectzebrafish
dc.titleEnvironmental pollutant sodium omadine: toxic effects in zebra fish (Danio rerio)
dc.typeArticle

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