TAFI gene polymorphisms in patients with cerebral venous thrombosis
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Date
2013
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Heidelberg
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Gene polymorphisms of thrombin activatable fibrinolysis inhibition (TAFI) factor have been investigated in various studies in terms of etiology (recurrence) and treatment (fibrinolytic effect) of thrombus formation. Cerebral venous thrombosis (CVT) is a life-threatening disease observed in young persons. Fifty-nine patients with CVT and 100 healthy control subjects were enrolled in the case/control study. The association between TAFI gene polymorphisms -438G > A, +505A > G and +1040C > T and cerebral venous thrombosis was investigated. It was found that frequencies of polymorphic genotype and allele were not different in patients than in control group and that they were not significant for cerebral venous thrombosis.
Description
Keywords
TAFI, Cerebral venous thrombosis, 438G > A, 505A > G, 1040C > T, Sinus thrombosis
Journal or Series
Acta Neurologica Belgica
WoS Q Value
Q3
Scopus Q Value
Q2
Volume
113
Issue
3
