A novel glucose biosensor platform based on Ag@AuNPs modified graphene oxide nanocomposite and SERS application

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dc.authoridEryilmaz, Merve/0000-0003-3034-7665
dc.authoridTamer, Ugur/0000-0001-9989-6123
dc.authoridAtar, Necip/0000-0001-8779-1412
dc.authoridUstundag, Zafer/0000-0002-5550-106X
dc.contributor.authorGupta, Vinod Kumar
dc.contributor.authorAtar, Necip
dc.contributor.authorYola, Mehmet Lutfi
dc.contributor.authorEryilmaz, Merve
dc.contributor.authorTorul, Hilal
dc.contributor.authorTamer, Ugur
dc.contributor.authorBoyaci, Ismail Hakki
dc.date.accessioned2025-03-23T19:41:18Z
dc.date.available2025-03-23T19:41:18Z
dc.date.issued2013
dc.departmentSinop Üniversitesi
dc.description.abstractThis study represents a novel template demonstration of a glucose biosensor based on mercaptophenyl boronic acid (MBA) terminated Ag@AuNPs/graphene oxide (Ag@AuNPs-GO) nanomaterials. The nanocomposites were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD) method. The TEM image shows that Ag@AuNPs in the nanocomposite is in the range of diameters of 10-20 nm. The nanocomposite was used for the determination of glucose through the complexation between boronic acid and diol groups of glucose. Thus, a novel glucose biosensor was further fabricated by immobilizing glucose oxidase (GOD) into MBA terminated Ag@AuNPs-GO nanocomposite film (MBA-Ag@AuNPs-GO). The linearity range of glucose was obtained as 2-6 mM with detection limit of 0.33 mM. The developed biosensor was also applied successfully for the determination of glucose in blood samples. The concentration value of glucose in blood samples was calculated to be 1.97 +/- 0.002 mM from measurements repeated for six times. (C) 2013 Elsevier Inc. All rights reserved.
dc.description.sponsorshipScientific and Technological Research Council of Turkey [111T983]
dc.description.sponsorshipThe authors are grateful for the financial support provided by The Scientific and Technological Research Council of Turkey; Project Number: 111T983.
dc.identifier.doi10.1016/j.jcis.2013.06.007
dc.identifier.endpage237
dc.identifier.issn0021-9797
dc.identifier.issn1095-7103
dc.identifier.pmid23816220
dc.identifier.scopus2-s2.0-84880145547
dc.identifier.scopusqualityQ1
dc.identifier.startpage231
dc.identifier.urihttps://doi.org/10.1016/j.jcis.2013.06.007
dc.identifier.urihttps://hdl.handle.net/11486/6546
dc.identifier.volume406
dc.identifier.wosWOS:000322094300028
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Science
dc.relation.ispartofJournal of Colloid and Interface Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectGraphene oxide
dc.subjectAg@AuNPs
dc.subjectCharacterization
dc.subjectGlucose biosensor
dc.subjectSERS
dc.titleA novel glucose biosensor platform based on Ag@AuNPs modified graphene oxide nanocomposite and SERS application
dc.typeArticle

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