Molecular imprinted nanosensor based on surface plasmon resonance: Application to the sensitive determination of amoxicillin

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dc.authoridAtar, Necip/0000-0001-8779-1412
dc.contributor.authorYola, Mehmet Lutfi
dc.contributor.authorEren, Tanju
dc.contributor.authorAtar, Necip
dc.date.accessioned2025-03-23T19:37:54Z
dc.date.available2025-03-23T19:37:54Z
dc.date.issued2014
dc.departmentSinop Üniversitesi
dc.description.abstractIn this report, we developed surface plasmon resonance (SPR) sensor for the sensitive determination of amoxicillin (AMOX) in chicken egg and human plasma. Firstly, the modification of gold surface of SPR chip was performed by allyl mercaptane. Then, AMOX-imprinted poly(2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid) [p(HEMAGA)] nanofilm was generated on the allyl mercaptane modified gold surface. The unmodified and imprinted surfaces were characterized by fourier transform infrared (FTIR) spectroscopy, ellipsometry and contact angle measurements. The developed method was validated according to the ICH guideline. The linearity range and the detection limit were obtained as 0.1-2.0 ng/mL and 0.022 ng/mL, respectively. The developed imprinted nanosensor was applied to the chicken egg and human plasma samples for the determination of AMOX. In addition, isotherm models were applied to data to explain adsorption process. (C) 2014 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.snb.2014.01.011
dc.identifier.endpage35
dc.identifier.issn0925-4005
dc.identifier.scopus2-s2.0-84893046500
dc.identifier.scopusqualityN/A
dc.identifier.startpage28
dc.identifier.urihttps://doi.org/10.1016/j.snb.2014.01.011
dc.identifier.urihttps://hdl.handle.net/11486/6041
dc.identifier.volume195
dc.identifier.wosWOS:000332417600005
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofSensors and Actuators B-Chemical
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectAmoxicillin
dc.subjectSPR
dc.subjectMolecular imprinting
dc.subjectValidation
dc.subjectNanosensor
dc.titleMolecular imprinted nanosensor based on surface plasmon resonance: Application to the sensitive determination of amoxicillin
dc.typeArticle

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