Boric acid complexes with thiamine (vitamin B1) and pyridoxine (vitamin B6)

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dc.authoridSahin, Onur/0000-0003-3765-3235
dc.contributor.authorKose, Dursun Ali
dc.contributor.authorZumreoglu-Karan, Birgul
dc.contributor.authorSahin, Onur
dc.contributor.authorBuyukgungor, Orhan
dc.date.accessioned2025-03-23T19:41:31Z
dc.date.available2025-03-23T19:41:31Z
dc.date.issued2014
dc.departmentSinop Üniversitesi
dc.description.abstractComplexation of boric acid with vitamins B1 (thiamine) and B6 (pyridoxine) was investigated. The products were isolated from aqueous solutions and characterized by elemental analysis, FT-IR, C-13 MAS NMR and thermal methods. The results of chemical and spectral analyses suggested that the reaction between thiaminechloride hydrochloride and H3BO3 in water yielded a salt-like productwith no direct bonding of the thiamine cation to boron while mono- and bis-chelate complexes were obtained with pyridoxine. The bis-chelate pyridoxine complex containing two equivalent pyridoxine ligands was obtained in crystal form. X-ray crystallography verified that complexation with boric acid occurs through the deprotonated phenolic and deprotonated adjacent alcoholic oxygen atoms forming six membered chelate rings. The negative charge on tetrahedral boron is balanced by the sodium ion. The crystal structure contains discernible tunnels parallel to the [010] direction constructed by hydrogen bonded complex molecules. (c) 2014 Elsevier B.V. All rights reserved.
dc.description.sponsorshipHacettepe University [06 D 02 1002]
dc.description.sponsorshipThe authors acknowledge Roche Chemicals/Istanbul for the kind donation of Pyridoxine Hydrochloride and Thiamine Chloride Hydrochloride. This work has been supported by Hacettepe University (Project 06 D 02 1002).
dc.identifier.doi10.1016/j.ica.2013.12.045
dc.identifier.endpage83
dc.identifier.issn0020-1693
dc.identifier.issn1873-3255
dc.identifier.scopus2-s2.0-84893915865
dc.identifier.scopusqualityQ2
dc.identifier.startpage77
dc.identifier.urihttps://doi.org/10.1016/j.ica.2013.12.045
dc.identifier.urihttps://hdl.handle.net/11486/6602
dc.identifier.volume413
dc.identifier.wosWOS:000332521000011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofInorganica Chimica Acta
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectBoric acid
dc.subjectBoron chelate
dc.subjectBorate ester
dc.subjectThiamine
dc.subjectPyridoxine
dc.subjectCrystal structure
dc.titleBoric acid complexes with thiamine (vitamin B1) and pyridoxine (vitamin B6)
dc.typeArticle

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