Combined effect of phosphorus, magnesium, yeast extract on lipid productivity of Yarrowia lipolytica grown with molasses

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dc.authoridPolat, Ece/0000-0001-7173-9126
dc.contributor.authorPolat, Ece
dc.contributor.authorYorucu, Gizem
dc.contributor.authorAltinbas, Mahmut
dc.date.accessioned2025-03-23T19:42:38Z
dc.date.available2025-03-23T19:42:38Z
dc.date.issued2022
dc.departmentSinop Üniversitesi
dc.description.abstractInadequate global fossil fuel reserves have forced researchers to investigate alternative fuel sources, and oleaginous microorganisms have attracted attention with their potential. Since high lipid production yield is an important criterion for suitable fuel production, in this study an oleaginous yeast, Yarrowia lipolytica, was selected and the lipid and biomass productivity under molasses (M20) substrate and nutrient supplementation was investigated. The effect of phosphorus as dipotassium hydrogen phosphate (K2HPO4), magnesium as magnesium sulphate (MgSO4), and yeast extract supplementation to molasses (M20) were evaluated individually and in combination. In addition, two quadratic models, using Box-Wilson central composite design, were used to correlate the phosphorus, magnesium and yeast extract concentrations that would achieve the highest biomass and lipid productivity. The study has shown that molasses (M20) supplemented with 336 mg/L K2HPO4, 0.17 g/L MgSO4 and 4.54 g/L yeast extract had the highest biomass productivity (80.7 mg/L/hour) and the highest lipid productivity (28.3 mg/L/hour). These productivity results were 1.44-fold and 2.42-fold higher than those of yeast extract-peptone-dextrose (YPD) broth, respectively. With enhanced biomass and lipid productivity, Yarrowia lipolytica can thus be used effectively in the fermentation industry.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [115Y349]
dc.description.sponsorshipThis work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) for financial support. Project no: 115Y349. We would like to thank Prof. Dr. Esra Capanolu Guven and Research Assistant Duygu Ceylan for the sugar content analysis of molasses.
dc.identifier.doi10.1007/s11814-022-1186-0
dc.identifier.endpage2753
dc.identifier.issn0256-1115
dc.identifier.issn1975-7220
dc.identifier.issue10
dc.identifier.scopus2-s2.0-85137996100
dc.identifier.scopusqualityQ2
dc.identifier.startpage2743
dc.identifier.urihttps://doi.org/10.1007/s11814-022-1186-0
dc.identifier.urihttps://hdl.handle.net/11486/6816
dc.identifier.volume39
dc.identifier.wosWOS:000846224500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKorean Institute Chemical Engineers
dc.relation.ispartofKorean Journal of Chemical Engineering
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectYarrowia lipolytica
dc.subjectMolasses
dc.subjectLipid Productivity
dc.subjectSurface Response Methodology
dc.titleCombined effect of phosphorus, magnesium, yeast extract on lipid productivity of Yarrowia lipolytica grown with molasses
dc.typeArticle

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