The relationship between admission immunoglobulin levels with the severity of the COVID-19 disease

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dc.authoridnalbant, ahmet/0000-0003-4756-3575
dc.authoridTor, Ibrahim Hakki/0000-0003-0246-3220
dc.authoridKaya, Tezcan/0000-0003-0483-2333
dc.authoridUsanmaz, Mustafa/0000-0002-5369-2560
dc.contributor.authorErgenc, Zeynep
dc.contributor.authorErgenc, Hasan
dc.contributor.authorOzturk, Ahmet
dc.contributor.authorKaya, Tezcan
dc.contributor.authorNalbant, Ahmet
dc.contributor.authorKaracaer, Cengiz
dc.contributor.authorUsanmaz, Mustafa
dc.date.accessioned2025-03-23T19:25:47Z
dc.date.available2025-03-23T19:25:47Z
dc.date.issued2024
dc.departmentSinop Üniversitesi
dc.description.abstractAim: The aim of this study is to investigate relationship between immunoglobin (Ig) levels and severity of COVID-19 disease. Material and Methods: The study was carried out at Ayancik State Hospital. Ethics committee approval was obtained before starting the study. Patients who applied to Ayancik State Hospital between 2021-2022 and were diagnosed with COVID-19 over the age of 19 were included in the study. Data on demographic and laboratory parameters of patients were obtained from hospital information system records. Patient files with additional information were not included in the study. Demographic data, laboratory parameters and immunoglobulin levels of patients with severe and mild COVID-19 disease were compared. Results: Of the patients diagnosed with COVID-19 included in the study, 28 (43.8%) were male and 36 (56.3%) were female. When the patients were evaluated according to age group, 44 (68.8%) were <65 years old and 20 (31.3%) were >65 years old. There was no significant difference between the severity of COVID-19 disease and the distribution of patients by gender and age group (respectively, p=0.208; p=0.059. There was a statistically significant difference in IgA, IgG, and IgM measurements between those with mild and severe disease (Respectively, p=0.001, p=0.001, p=0.011). IgA (2.33), IgG (12.19) and IgM (1.31) measurements were higher in those with mild COVID-19 disease. Discussion: The results showed that immunoglobulin indices were significantly lower in patients with severe COVID-19. Therefore, the lack of immunoglobulin can be considered an indicator of the severity of the disease and the potential poor outcome of the disease.
dc.identifier.doi10.4328/ACAM.21731
dc.identifier.endpage224
dc.identifier.issn2667-663X
dc.identifier.issue4
dc.identifier.scopusqualityN/A
dc.identifier.startpage221
dc.identifier.urihttps://doi.org/10.4328/ACAM.21731
dc.identifier.urihttps://hdl.handle.net/11486/4566
dc.identifier.volume15
dc.identifier.wosWOS:001206199400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherBayrakol Medical Publisher
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250323
dc.subjectCOVID-19
dc.subjectImmunoglobulin
dc.subjectIgA
dc.subjectIgG
dc.subjectIgM
dc.titleThe relationship between admission immunoglobulin levels with the severity of the COVID-19 disease
dc.typeArticle

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