The relationship between admission immunoglobulin levels with the severity of the COVID-19 disease
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Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bayrakol Medical Publisher
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The aim of this study is to investigate relationship between immunoglobin (Ig) levels and severity of COVID-19 disease. Material and Methods: The study was carried out at Ayancik State Hospital. Ethics committee approval was obtained before starting the study. Patients who applied to Ayancik State Hospital between 2021-2022 and were diagnosed with COVID-19 over the age of 19 were included in the study. Data on demographic and laboratory parameters of patients were obtained from hospital information system records. Patient files with additional information were not included in the study. Demographic data, laboratory parameters and immunoglobulin levels of patients with severe and mild COVID-19 disease were compared. Results: Of the patients diagnosed with COVID-19 included in the study, 28 (43.8%) were male and 36 (56.3%) were female. When the patients were evaluated according to age group, 44 (68.8%) were <65 years old and 20 (31.3%) were >65 years old. There was no significant difference between the severity of COVID-19 disease and the distribution of patients by gender and age group (respectively, p=0.208; p=0.059. There was a statistically significant difference in IgA, IgG, and IgM measurements between those with mild and severe disease (Respectively, p=0.001, p=0.001, p=0.011). IgA (2.33), IgG (12.19) and IgM (1.31) measurements were higher in those with mild COVID-19 disease. Discussion: The results showed that immunoglobulin indices were significantly lower in patients with severe COVID-19. Therefore, the lack of immunoglobulin can be considered an indicator of the severity of the disease and the potential poor outcome of the disease.
Açıklama
Anahtar Kelimeler
COVID-19, Immunoglobulin, IgA, IgG, IgM
Kaynak
Annals of Clinical and Analytical Medicine
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
15
Sayı
4
