Prediction of electron density and trace element concentrations in human blood serum following radioiodine therapy in differentiated thyroid cancer patients

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dc.authoridKARABUL, YASAR/0000-0002-0789-556X
dc.authoridDemir, Mustafa/0000-0002-9813-1628
dc.authoridBURSALIOGLU, Ertugrul Osman/0000-0002-2882-7435
dc.contributor.authorBursalioglu, Ertugrul O.
dc.contributor.authorAlkan, Fatma A.
dc.contributor.authorBarutcu, Umit B.
dc.contributor.authorDemir, Mustafa
dc.contributor.authorKarabul, Yasar
dc.contributor.authorBalkan, Begum
dc.contributor.authorOz, Ersoy
dc.date.accessioned2025-03-23T19:40:55Z
dc.date.available2025-03-23T19:40:55Z
dc.date.issued2017
dc.departmentSinop Üniversitesi
dc.description.abstractThe aim of this study is to investigate trace element levels (Cr, Cu, Fe, Mg, Mn, Se, Zn, As, B, Si and Co) in serum samples of patients with papillary thyroid cancer. The analysis of trace elements levels of samples carried out using ICP-OES. Elements in blood samples were determined by ICP-OES after using Hettich Universal Centrifuge and differences between the values of Zn, Mg, Fe and Cu of blood samples were obtained pre -therapy and post -therapy. The concentrations of elements were normalized to percentage. Later, electron densities (N-el) of blood samples have been determined using ZXCOM program. A venture was made to perform a correlation between electron density and pre -posttreatment. This attempt is quite new in literature. Interestingly, it was generally observed that the electron densities of blood samples posttreatment are higher than pretreatment. Among elements, normalized concentration values of Cu and electron densities were in particular compared with patient type. Also, statistical analysis of blood results was achieved for 11 patients and 11 normal individual as control group for pre-posttreatment. Wilcoxon test which is a non -parametric test was used. 2016 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.measurement.2016.12.035
dc.identifier.endpage25
dc.identifier.issn0263-2241
dc.identifier.issn1873-412X
dc.identifier.scopus2-s2.0-85007496584
dc.identifier.scopusqualityQ3
dc.identifier.startpage19
dc.identifier.urihttps://doi.org/10.1016/j.measurement.2016.12.035
dc.identifier.urihttps://hdl.handle.net/11486/6452
dc.identifier.volume100
dc.identifier.wosWOS:000394397600003
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofMeasurement
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectElements
dc.subjectMinerals
dc.subjectThyroid cancer
dc.subjectBlood samples
dc.subjectElectron density
dc.subjectICP-OES
dc.titlePrediction of electron density and trace element concentrations in human blood serum following radioiodine therapy in differentiated thyroid cancer patients
dc.typeArticle

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