Synthesis and characterization of 4-hydroxy-3-((2-hydroxy-3-methoxyben-zylidene)amino)benzene-sulfonic acid and its metal complexes and their antimicrobial activity

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dc.authoridOzkinali, Sevil/0000-0001-9166-191X
dc.authoridVeyisoglu, Aysel/0000-0002-1406-5513
dc.contributor.authorYavuz, Senol
dc.contributor.authorKose, Dursun Ali
dc.contributor.authorOzkinali, Sevil
dc.contributor.authorTatar, Demet
dc.contributor.authorVeyisoglu, Aysel
dc.date.accessioned2025-03-23T19:39:17Z
dc.date.available2025-03-23T19:39:17Z
dc.date.issued2025
dc.departmentSinop Üniversitesi
dc.description.abstractSchiff base was obtained from the reaction of vanillin with 3-amino-4-hydroxybenzenesulfonic acid. Metal complexes were synthesized using (Ni(NO3)2, Co(NO3)2, Mn(NO3)2, Cu(NO3)2, Zn(NO3)2) metal salts and the structures of the compounds were elucidated by spectroscopic methods. The structures of the metal complexes were also characterized by elemental analysis, FT-IR, thermogravimetric analysis and magnetic susceptibility analysis and their antimicrobial activities were investigated. The antimicrobial activities of the obtained coordination compounds were investigated against three Gram-positive (Bacillus subtilis ATCC 6633; Staphylococcus aureus ATCC 25923; Enterococcus faecalis ATCC 29212) three Gram-negative bacterial (Escherichia coli ATCC 25922; Klebsiella pneumonia ATCC 70060; Pseudomonas aeruginosa ATCC 27853) strains and two fungal (Aspergillus niger ATCC 16404; Candida albicans ATCC 1023) strains, and the minimum inhibitory concentration (MIC) values were determined. According to the MIC values, the SC-Ni complex exhibited the highest antimicrobial activity, while the SC-Cu complex showed the lowest.
dc.description.sponsorshipHitit University Scientific Research Projects Unit [ODMYO19001.20.002]
dc.description.sponsorshipResearchers accept the study to Hitit University Scientific Research Projects Unit, which provides financial support with the project code ODMYO19001.20.002
dc.identifier.doi10.1016/j.molstruc.2024.140364
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85207003561
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2024.140364
dc.identifier.urihttps://hdl.handle.net/11486/6311
dc.identifier.volume1322
dc.identifier.wosWOS:001343659900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectVanillin
dc.subjectSchiff bases
dc.subjectImine group
dc.subjectMetal complexes
dc.subjectAntimicrobial activity
dc.titleSynthesis and characterization of 4-hydroxy-3-((2-hydroxy-3-methoxyben-zylidene)amino)benzene-sulfonic acid and its metal complexes and their antimicrobial activity
dc.typeArticle

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