The effects of long-term oxygen therapy on survey in patients with chronic respiratory failure

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dc.contributor.authorDuzenli, Hasan
dc.contributor.authorDogan, Omer Tamer
dc.contributor.authorBerk, Serdar
dc.contributor.authorOzsahin, Sefa Levent
dc.contributor.authorAkkurt, Ibrahim
dc.date.accessioned2025-03-23T19:48:30Z
dc.date.available2025-03-23T19:48:30Z
dc.date.issued2008
dc.departmentSinop Üniversitesi
dc.description.abstractLong-term (>= 15 hours) oxygen therapy (LTOT) increases life-span and improves quality of life (QOL) in patients with chronic respiratory failure (CRF). However, in our clinical practice, we observed that very few patients are using oxygen therapy 15 hours or more. Furthermore, very few literatures about survival of non-or inadequate oxygen users were found. Thus, the aim of this study was to assess the effect of LTOT in patients with CRF. A total of 305 LTOT recommended patients with CRF in our clinic between 1996 and 2001 were found. A hundred and five patients with documented subject characteristics were included the study and followed-up similar to 20 months prospectively. They were divided into two groups whether to take LTOT (group 1, n= 71) or not (group 2, n= 34). Average life-span of the patients was 50 months in group 1 and 39 months in group 2 (p< 0.05). Survival (months) in group 1 was significantly correlated with hrs of oxygen use (r= 0.684, p= 0.001). One more hour oxygen use was statistically significantly correlated with 0.002 months more survival (F= 48.44, p< 0.05) in group 1 in logistic regression analysis. In comparisons, there were significant improvement in the post-treatment blood gas values in group 1 (p< 0.05). There were significant decreases in PFT values in the post-treatment period when compared to baseline values in both groups (p< 0.05). There was a less decrease in FEV1 values per year in group 1 than group 2 but difference was not statistically significant (p> 0.05). In conclusion our findings revealed that LTOT provides improvement of the life-span of the patients with CRF.
dc.identifier.endpage186
dc.identifier.issn0494-1373
dc.identifier.issue2
dc.identifier.pmid18701978
dc.identifier.scopusqualityQ3
dc.identifier.startpage179
dc.identifier.urihttps://hdl.handle.net/11486/7606
dc.identifier.volume56
dc.identifier.wosWOS:000421237500007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isotr
dc.publisherTurkish Assoc Tuberculosis & Thorax
dc.relation.ispartofTuberkuloz Ve Torak-Tuberculosis and Thorax
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectLTOT
dc.subjectrespiratory failure
dc.subjectlife-span
dc.titleThe effects of long-term oxygen therapy on survey in patients with chronic respiratory failure
dc.typeArticle

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