Oxytocin imprinted polymer based surface plasmon resonance sensor and its application to milk sample

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dc.authoridAtar, Necip/0000-0001-8779-1412
dc.authoridErdem Gursan, K. Arzum/0000-0002-4375-8386
dc.contributor.authorYola, Mehmet Lutfi
dc.contributor.authorAtar, Necip
dc.contributor.authorErdem, Arzum
dc.date.accessioned2025-03-23T19:37:52Z
dc.date.available2025-03-23T19:37:52Z
dc.date.issued2015
dc.departmentSinop Üniversitesi
dc.description.abstractIn present study, a novel and sensitive molecular imprinted surface plasmon resonance sensor was prepared by fabricating a self-assembling monolayer formation of allylmercaptane on gold chip surface for selective determination of oxytocin in milk. Then, oxytocin-imprinted poly (2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid) nanofilm was performed onto the allyl mercaptane modified chip. The unmodified and modified surfaces were characterized by using Fourier transform infrared spectroscopy, atomic force microscopy, ellipsometry, scanning electron microscope and contact angle measurements. The imprinted surface plasmon resonance sensor was found to be sensitive, selective, linear and proper. The linearity range in the concentration range of oxytocin was obtained as 0.01-1.0 ng/mL and the detection limit of the prepared sensor was calculated as 0.0030 ng/mL. The molecular imprinted sensor based on surface plasmon resonance was also applied successfully to milk sample for the determination of oxytocin. Furthermore, the repeatability of the prepared molecular imprinted sensor was studied. The good repeatability of the prepared oxytocin-imprinted surface plasmon resonance sensors makes them attractive in sensor studies. In addition, isotherm models were applied to data to explain adsorption process. (C) 2015 Elsevier B.V. All rights reserved.
dc.description.sponsorshipDumlupinar University; Pamukkale University; [2014HZL023]
dc.description.sponsorshipAuthors thank Dumlupinar University and Pamukkale University for the equipments and also the financial support through by project grant (Project No: 2014HZL023).
dc.identifier.doi10.1016/j.snb.2015.07.004
dc.identifier.endpage848
dc.identifier.issn0925-4005
dc.identifier.scopus2-s2.0-84938149496
dc.identifier.scopusqualityQ1
dc.identifier.startpage842
dc.identifier.urihttps://doi.org/10.1016/j.snb.2015.07.004
dc.identifier.urihttps://hdl.handle.net/11486/6036
dc.identifier.volume221
dc.identifier.wosWOS:000362918100109
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofSensors and Actuators B-Chemical
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectOxytocin
dc.subjectSurface plasmon resonance
dc.subjectMolecular imprinting
dc.subjectValidation
dc.titleOxytocin imprinted polymer based surface plasmon resonance sensor and its application to milk sample
dc.typeArticle

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