Synthesis of some new Methoxy Bridged Benzimidazolyl-Substituted phthalocyanines as potent inhibitors of urease

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dc.authoridBayrak, Riza/0000-0002-0398-7694
dc.authoridAKCAY, Hakki Turker/0000-0002-8502-9608
dc.contributor.authorDemirbas, Umit
dc.contributor.authorMentese, Emre
dc.contributor.authorSokmen, Bahar Bilgin
dc.contributor.authorBayrak, Riza
dc.contributor.authorAkcay, Hakki Turker
dc.date.accessioned2025-03-23T19:40:59Z
dc.date.available2025-03-23T19:40:59Z
dc.date.issued2018
dc.departmentSinop Üniversitesi
dc.description.abstractIn this study, the novel peripherally 4-[(2-methyl-1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4), Co(II) (5) phthalocyanines were prepared and their structures were characterized spectro-scopically. The light absorption behaviors of the synthesized compounds (3-6) were studied by UV-Vis spectroscopy in the different concentration and different solvents were studied also. In addition, the urease inhibition activities of the synthesized compounds were also investigated. Among the synthesized molecules, compound 5 showed the best inhibitory effect against jack bean urease with IC50 values of 0.0034 +/- 0.0010 mu M. (C) 2018 Elsevier B.V. All rights reserved.
dc.description.sponsorshipRecep Tayyip Erdogan Universitesi - Research Funding [FBA-2017-788]
dc.description.sponsorshipThis study was supported by Recep Tayyip Erdogan Universitesi - Research Funding - (Project no FBA-2017-788).
dc.identifier.doi10.1016/j.jorganchem.2018.08.001
dc.identifier.endpage90
dc.identifier.issn0022-328X
dc.identifier.issn1872-8561
dc.identifier.scopus2-s2.0-85051622790
dc.identifier.scopusqualityQ2
dc.identifier.startpage86
dc.identifier.urihttps://doi.org/10.1016/j.jorganchem.2018.08.001
dc.identifier.urihttps://hdl.handle.net/11486/6484
dc.identifier.volume873
dc.identifier.wosWOS:000443574000012
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofJournal of Organometallic Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250323
dc.subjectPhthalocyanine
dc.subjectElectronic absorption
dc.subjectAggregation
dc.subjectUrease inhibition activity
dc.titleSynthesis of some new Methoxy Bridged Benzimidazolyl-Substituted phthalocyanines as potent inhibitors of urease
dc.typeArticle

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