Spectral characterization and antimicrobial activity studies of 5,6-dichloro-1H-benzimidazol-2-yl-(4'/5'/6'-substituted)-phenols (HL1-HL20) and Co(II), Ni(II), Cu(II), Zn(II) and Pd(II) complexes of HL1

Basit Öğe Kaydı
dc.contributor.authorTavman, Aydin
dc.contributor.authorGurbuz, Demet
dc.contributor.authorHacioglu, Mayram
dc.contributor.authorCinarli, Adem
dc.contributor.authorSahin, Onur
dc.contributor.authorTan, A. Seher Birteksoz
dc.date.accessioned2026-04-25T14:20:25Z
dc.date.available2026-04-25T14:20:25Z
dc.date.issued2026
dc.departmentSinop Üniversitesi
dc.description.abstract5,6-Dichloro-1H-benzimidazol-2-yl-(4'/5'/6'-substituted)-phenols (HL1-HL20) and MCl2 complexes (M: Co, Ni, Cu, Zn, Pd) of HL1 were synthesized and characterized by various physicochemical and spectroscopic methods such as elemental analysis, thermogravimetric analysis, FTIR, NMR and fluorescence spectroscopy. The structures of the complexes were also confirmed by performing molar conductivity and magnetic moment measurements. HL1 acted as a bidentate, monobasic chelating ligand with NO donor sites in all the complexes. It was found that all complexes have non-electrolytic properties and the M:L ratios are 1:1 in the Zn(II) complex and 1:2 in the other complexes. Crystal structure of HL18 was also investigated. The presence of both intra-and inter-molecular hydrogen bonding was observed in both molecules. According to the fluorescence spectral data, the substituents at the 4-position made the fluorescence emission shifted to the lower wavelengths (redshift) compared to HL1, while the substituents at the 3-and 5-positions caused a blue shift effect. The Zn(II) complex showed a greater redshift effect compared to the other complexes. In addition, antimicrobial activity of the compounds was evaluated against six bacteria and three fungi. It was observed that HL1 and its mono substituted derivatives (HL1-HL11) show selective activity especially against Gram-positive bacteria, Staphylococcus aureus and Staphylococcus epidermidis. Zn(II) complex showed relatively higher activity against Gram-positive bacteria differently from the other complexes.
dc.description.sponsorshipScientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa [24777]
dc.description.sponsorshipAcknowledgement. This work was supported by Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa, Project number: 24777.
dc.identifier.doi10.2298/JSC250806078T
dc.identifier.endpage127
dc.identifier.issn0352-5139
dc.identifier.issue2
dc.identifier.orcid0000-0003-0823-631X
dc.identifier.orcid0000-0003-3765-3235
dc.identifier.scopus2-s2.0-105033455033
dc.identifier.scopusqualityQ3
dc.identifier.startpage113
dc.identifier.urihttps://doi.org/10.2298/JSC250806078T
dc.identifier.urihttps://hdl.handle.net/11486/8551
dc.identifier.volume91
dc.identifier.wosWOS:001686313200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSerbian Chemical Soc
dc.relation.ispartofJournal of The Serbian Chemical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260420
dc.subjectbenzimidazolylphenol
dc.subjecthalogen
dc.subjecttransition metal complexes
dc.subjectantibac-terial
dc.subjectantifungal
dc.titleSpectral characterization and antimicrobial activity studies of 5,6-dichloro-1H-benzimidazol-2-yl-(4'/5'/6'-substituted)-phenols (HL1-HL20) and Co(II), Ni(II), Cu(II), Zn(II) and Pd(II) complexes of HL1
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu