Effect of Cow Colostrum, Mare Milk, and Human Milk on the Viability of Lung Healthy and Cancer Cell Lines
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Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dubai Iranian Hosp
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study investigated the effects of lyophilized mare milk, human milk, and cow colostrum on both human lung cancer cell line called A549, and healthy lung cell line called MRC5. Mare milk, human milk, and cow colostrum varieties were applied to 6 replicates in both cell lines with lyophilized milk concentrations ranging from 50 - 3200 ppm. The cell viability was monitored by optic microscopy and determined by the MTT test. ANOVA and Duncan's multiple range tests were used to analyze data. The results of this study indicated that the most effective milk type on reducing the A549 lung cancer cell line was human milk, followed by mare milk; however, cow colostrum showed little effect. It was observed that human milk and mare milk had anti-proliferative effects on lung cancer cell line at concentrations which were non-toxic to healthy lung cell line.
Açıklama
Anahtar Kelimeler
Cell viability, Colostrum, Cow milk, Human milk, Mare milk
Kaynak
Iranian Red Crescent Medical Journal
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
23
Sayı
5
