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    Synthesis, characterization, and investigations of antimicrobial activity of benzopyrans, benzofurans and spiro[4.5]decanes
    (Taylor & Francis Inc, 2018) Akpinar, Deniz E.; Ozgur (Nee Yakut), Mehtap; Aslan, Hakan; Alagoz, Oguzhan; Oktemer, Atilla; Dal, Hakan; Hokelek, Tuncer
    In this study, the radical cyclization reactions of cyclic 1,3-dicarbonyl compounds (1a-c) and a, b-unsaturated alcohols (2a-d) through Mn(OAc) 3 were performed. A series of biologically interesting dihydropyrans (3-5) and dihydrofurans (6-18) were synthesized as a result of these reactions. Spiro compounds (19-20) were obtained from the reactions of 1,3-dicarbonyl compounds and (E)-2,4-diphenyl-but-3-en2-ol (2e). The unique structure of compound 19 was also confirmed by X-ray crystallography. In addition, the antibacterial activities of synthesized compounds were screened against some bacteria. Their zone diameters showed better results than some known antibiotics.