Yazar "Yagmur, Isil" seçeneğine göre listele

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    Öğe
    Evaluation of Oxidative Stress Parameters in Male Textile Workers Working in Different Sections of Production
    (Kahramanmaras Sütçü Imam Üniversitesi, 2024) Dokumaci, Leyla; Yagmur, Isil; Tural, Rabia; İnanç Tolun, Fatma; Dagli, Hasan; Doboglu, Yeliz; Sager, Hatice
    Objective: Occupationally exposed environmental conditions and many substances threaten human health by causing diseases. This study examines biochemically how the oxidant and antioxidant system parameters change in the employees working in different textile departments.Material and Methods:3 groups of 30 people were formed, each consisting of healthy men who do not smoke or drink alcohol, working in the office, dyehouse and yarn departments of a textile company in Kahramanmaras office worker (control group, group 1), dyehouse worker (group 2), yarn worker (group 3). After 12 hours of fasting, venous blood samples were taken and serum samples were separated. Total oxidant status (TOS), total antioxidant status (TAS), total thiol
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    Öğe
    Protective effect of Asphodelus aestivus Brot. on bladder injury due to ischemia-reperfusion: Biochemical and histopathological Study
    (Natl Inst Science Communication-Niscair, 2025) Kopar, Hatice; Yagmur, Isil; Kurutas, Ergul Belge; Tural, Rabia
    Severe oxidative stress caused by reperfusion after ischemia in the bladder causes serious functional and structural damage. New molecules with antioxidant effects are needed to protect against this damage. In our study, we aimed to investigate the effect of Asphodelus aestivus on the oxidant-antioxidant system in bladder ischemia/reperfusion (I/R) injury induced in rats biochemically and histopathologically. In our study, 24 three-month-old male Wistar-Albino rats weighing 250-300 g were randomly divided into 3 groups of 8 rats each: sham group (I/R+serum physiological, 1mL) (group 1), I/R group (group 2), I/R+A. aestivus group (50 mg/kg/day) (treatment group, group 3). At the end of the experiment, all rats were sacrificed and their bladder tissues were taken and divided into 2 parts for biochemical and histopathological examination. Protein amount, malondialdehyde (MDA) levels and superoxide dismutase (SOD) and catalase (CAT) enzyme activity levels were measured spectrophotometrically, and histopathological examination was performed under a light microscope. MDA levels were significantly higher and CAT activity was significantly lower in the I/R group compared to the sham and treatment groups (P<0.05). In histopathological examination, it was determined that there was a significant regression and/or decrease in the findings caused by I/R injury in the group treated with A. aestivus. A. aestivus has a protective effect in reducing oxidative stress in bladder I/R injury.