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    Effects of Orange Oil Aromatherapy on Pain and Anxiety During Invasive Interventions in Patients With Hematopoietic Stem Cell Transplants
    (Lippincott Williams & Wilkins, 2024) Erdal, Seckin; Ozdogan, Merve Harman; Yildirim, Dilek; Kuni, Aysem; Selcuk, Sevinc; Guneri, Azize; Arslan, Elif Naz
    Invasive interventions, such as peripheral intravenous cannula, port needle placement, and blood collection, are often required for both inpatient and outpatient follow-up patients with hematological malignancies and hematopoietic stem cell transplants. This prospective, randomized controlled experimental study assessed the effect of orange oil inhalation used in aromatherapy on pain and anxiety levels in invasive interventions with hematological malignancies and hematopoietic stem cell transplants. It was conducted prospectively with 80 patients with hematological malignancies who were treated in the adult bone marrow transplant unit and adult hematology service of a private hospital between May 2021 and April 2022. The orange oil inhalation used in aromatherapy was applied to patients in the intervention group. The Visual Analog Scale (VAS) and State-Trait Anxiety Inventory (STAI) were used for data collection. Regarding the personal characteristics of the patients, 42.5% were >= 61 years old, 60% were men, and 85% were married. VAS pain scores of the intervention group were statistically lower than those of the control group (P < .001). However, there was no statistically significant difference in the STAI scores of groups (P >.05). The study results show that orange oil inhalation has been determined to reduce pain during invasive interventions.
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    EFFECTS OF ORANGE OIL AROMATHERAPY ON THE PAIN AND ANXIETY DURING INVASIVE INTERVENTIONS IN PATIENTS WITH HEMATOPOIETIC STEM CELL TRANSPLANTATION
    (Springernature, 2023) Erdal, Seckin; Ozdogan, Merve Harman; Yildirim, Dilek; Kuni, Aysem; Selcuk, Sevinc; Guneri, Azize; Arslan, Elif Naz
    [No abstract available]
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    The efficacy of lavender oil on fatigue and sleep quality in patients with hematological malignancy receiving chemotherapy: a single-blind randomized controlled trial
    (Springer, 2025) Yildirim, Dilek; Ozdogan, Merve Harman; Erdal, Seckin; Selcuk, Sevinc; Guneri, Azize; Simsek, Elif Begum; Can, Taha Berkay
    Purpose The aim of this study is to evaluate how aromatherapy with the inhalation of lavender oil affects fatigue and sleep quality in patients with hematological malignancies undergoing chemotherapy. Methods This randomized, parallel-group study was carried out in the Adult Bone Marrow Transplant unit and Hematology-Oncology clinics between January 2022 and April 2023. A total of 120 patients were assigned to experimental and control groups by randomization. The study was completed with 100 patients including 50 in the experimental group and 50 in the control group. Lavender essential oil was applied to the experimental group for 20 min prior to going to bed every night for 5 consecutive days. Physiological saline solution was applied to the control group in the same way. A Participant Information Form, the Richards-Campbell Sleep Questionnaire, and the Piper Fatigue Scale were used as data collection tools. Results The experimental group showed a significantly higher sleep quality (p = 0.001) and had a significantly lower PFS scores (p = 0.001) compared to the control group. Also, the mean scores of the experimental group on the Behavioral, Sensory, and Cognitive subscales were statistically significantly lower than the scores of the control group (p < 0.05). Variables of lavender aromatherapy and total sleep quality accounted for 17.1% of the variance in fatigue levels (R2 = 0.171). Conclusions Consequently, it was determined that aromatherapy with lavender essential oil significantly alleviated fatigue and lowered PFS total and subscale scores in patients with hematological malignancies undergoing chemotherapy. Also, sleep quality significantly enhanced in the overall PFS and its subscales. Trial registration.NCT05808296.