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    EFFECT OF ZINC SULPHATE ON THE LEVELS OF PLASMA PARAOXONASE ACTIVITY, TOTAL OXIDANT AND HIGH DENSITY LIPOPROTEIN OF TRANSCAUCASIAN BARB (Capoeta capoeta [Guldenstaedt, 1773])
    (Parlar Scientific Publications (P S P), 2015) Deveci, Haci Ahmet; Kaya, Inan; Yilmaz, Muhittin; Karapehlivan, Mahmut
    Zinc and its compounds have different effects in chemical or toxicological terms on many living species in the aquatic areas. In this study, total plasma paraoxonase activity (PON1), total oxidant (TOS) and high density lipoprotein (HDL) levels in response to different doses of zinc sulphate (ZnSO4) in Capoeta capoeta were investigated. The fishes were kept in tanks for 15 days for adaptation. Three groups of fish (control, 1st and 2nd), each containing nine fishes, were placed in separate tanks containing no 5 and 10 mg/L ZnSO4, respectively for 10 days. At the end of the study, blood samples were taken, and plasma PON1, TOS and HDL levels were analyzed. An increase in plasma TOS level was found along with increasing ZnSO4 amounts compared to the control group, and a decrease in PON1 and HDL levels was observed. In conclusion, it was determined that levels of PON1, TOS and BDL were altered depending on ZnSO4 doses applied in Capoeta capoeta.
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    Öğe
    Effect of zinc sulphate on the levels of plasma paraoxonase activity, total oxidant and high density lipoprotein of transcaucasian barb: (Capoeta capoeta [Guldenstaedt, 1773])
    (Parlar Scientific Publications, 2015) Deveci, Haci Ahmet; Kaya, Inan; Yilmaz, Muhittin; Karapehlivan, Mahmut
    Zinc and its compounds have different effects in chemical or toxicological terms on many living species in the aquatic areas. In this study, total plasma paraoxonase activity (PON1), total oxidant (TOS) and high density lipoprotein (HDL) levels in response to different doses of zinc sulphate (ZnSO4) in Capoeta capoeta were investigated. The fishes were kept in tanks for 15 days for adaptation. Three groups of fish (control, 1st and 2nd), each containing nine fishes, were placed in separate tanks containing no 5 and 10 mg/L ZnSO4, respectively for 10 days. At the end of the study, blood samples were taken, and plasma PON1, TOS and HDL levels were analyzed. An increase in plasma TOS level was found along with increasing ZnSO4 amounts compared to the control group, and a decrease in PON1 and HDL levels was observed. In conclusion, it was determined that levels of PON1, TOS and HDL were altered depending on ZnSO4 doses applied in Capoeta capoeta.
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    Öğe
    EFFECTS OF GLYPHOSATE (HERBICIDE) ON SERUM PARAOXONASE ACTIVITY, HIGH DENSITY LIPOPROTEIN, TOTAL ANTIOXIDANT AND OXIDANT LEVELS IN KARS CREEK TRANSCAUCASIAN BARBS (CAPOETA CAPOETA [GULDENSTAEDT, 1773])
    (Parlar Scientific Publications (P S P), 2017) Deveci, Haci Ahmet; Unal, Sevgi; Karapehlivan, Mahmut; Ayata, Muradiye Karasu; Gaffaroglu, Muhammet; Kaya, Inan; Yilmaz, Muhitdin
    The aim of this study is to explore the effects of the herbicide glyphosate on serum paraoxonase (PON1) activity, high-density lipoprotein (HDL), and total antioxidant (TAS) and oxidant (TOS) levels in Kars Creek Transcaucasian Barbs (Capoeta capoeta [Guldenstaedt, 1773]). Twenty four Capoeta capoeta are chosen within a weight range of 200 to 240 grams and they are equally divided into 3 groups, namely Groups I, II, III. The fish placed in Group I are received aquatic environment while Groups II and III were kept in aquatic environments with a pH value of 7.4 in tanks to which 0,01 and 0,02 mg/L glyphosate (N-phosphonomethyl glycine 480 mg/L), respectively. It was found that groups II and III had significantly lower serum plasma PON1, HDL and TAS levels than the control group (Group I). On the other hand, serum TOS levels were found significantly elevated in Groups II and III, in comparison to the control group. In this work, significant changes were found in the serum paraoxonase activity, HDL, TAS and TOS levels of fishes living in environments added 0.01 and 0.02 mg/L glyphosate.
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    The Effects of Carbaryl and 2,4-Dichlorophenoxyacetic Acid on Oxidative Stress Index in Capoeta capoeta (Guldensteadt 1773)
    (Zoological Soc Pakistan, 2019) Kaya, Inan; Yilmaz, Muhitdin; Kaya, Muge Mavioglu; Kukurt, Abdulsamed; Karapehlivan, Mahmut
    The aim of the present study is to investigate the oxidative stress index in Capoeta capoeta treated with carbaryl and 2,4-dichlorophenoxyacetic acid (2,4-D). Fifty Capoeta capoeta fish caught in Kars Creek were equally divided into five groups and acclimatized in separate tanks for 10 days. The fish were kept in tanks as follows: Group I (control) was kept in normal water. Group II, III, IV and V were kept in separate tanks containing 0.3 mg/L carbaryl, 0.6 mg/L carbaryl, 10 mg/L 2,4-D and 20 mg/L 2,4-D, respectively. The blood and liver samples were taken from the fish for biochemical studies at the end of the study period. Oxidative stress index (OSI) in plasma were evaluated as well as AST and ALT levels in the liver. Plasma OSI and liver AST levels in the groups with carbaryl and 2,4-D were compared with the control group, and they were found to be significantly higher. As a result, it was concluded that carbaryl and 2,4-D administered under of LC50 value caused liver damage by increasing the oxidative stress of Capoeta capoeta.