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    EFFECTS OF A PORPHYRAZINE DERIVATIVE ON SOME DEVELOPMENTAL CHARACTERISTICS OF DROSOPHILA MELANOGASTER
    (Akademiai Kiado Zrt, 2011) Karatas, Ayla; Ertan, Fatma; Saki, Neslihan; Baspinar, Ensar; Sevim, A. M.; Gul, A.
    In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphy-razinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F-1 and F-2 generation of Drosophila. Although individuals of F-2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.
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    Öğe
    The Effect of Diazinon on Puffing Activity in Polytene Chromosomes of Drosophila melanogaster
    (Foundation Environmental Protection & Research-Fepr, 2012) Karatas, Ayla; Bahceci, Zafer; Baspinar, Ensar
    This study investigates the effects of diazinon, an organic phosphoric insecticide, puffing on salivary gland polytene chromosomes of Drosophila melanogaster. Adult flies are applied diazinon and F1 generations were developed. The third instar larvae's salivary glands polytene chromosomes were examined in F1 generation. Puff areas in polytene chromosomes are regions of RNA synthesis and provide information on interphase nucleus. Certain differences were detected in puffing model of polytene chromosomes following he diazinon application. These differences were either the retreat of certain active regions or the activation of certain band regions. Puffs in 1D, 4C, 22AB, 38B, 63F, 71F, 72D, 74C, 97A, 97E, 98A, 98D, and 98E band regions retreated with diazinon application. On the other hand, active puff areas were detected in 1E, 2D, 3AB, 7AB, 42E, 43F, 57EF, 58EF, 61CD, 67AB, 72AB, 82D and 88F band regions after diazinon application. Some differences were observed in puffing frequency in some puff areas. In conclusion, it could be said, that diazinon application changed the interphase nucleus mechanism in polytene chromosomes, and thus the developmental program.