Karatas, AylaErtan, FatmaSaki, NeslihanBaspinar, EnsarSevim, A. M.Gul, A.2025-03-232025-03-2320110236-53831588-256Xhttps://doi.org/10.1556/ABiol.62.2011.4.8https://hdl.handle.net/11486/5022In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphy-razinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F-1 and F-2 generation of Drosophila. Although individuals of F-2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.eninfo:eu-repo/semantics/closedAccessPorphyrazineDrosophila melanogastertoxic effectsex ratioegg fertilityArticle62442644010.1556/ABiol.62.2011.4.8221198712-s2.0-82955201794N/AWOS:000297798600008N/A