Cakmak, SukriyeKansiz, SevgiAzam, MohammadVeyisoglu, AyselYakan, HasanMin, Kim2025-03-232025-03-2320222470-1343https://doi.org/10.1021/acsomega.2c00879https://hdl.handle.net/11486/5946We report a novel anhydride derivative, 3-acetoxy-2-methylbenzoic anhydride (AMA), obtained from the interaction of 3-acetoxy-2-methylbenzoyl chloride with 3-acetoxy-2-methylbenzoic acid. The synthesized compound was characterized by elemental analysis, IR, H-1 NMR, and C-13 NMR spectroscopic studies and single-crystal X-ray crystallography which revealed the crystallization of AMA as monoclinic with space group P2(1)/c. A Hirshfeld surface analysis was performed to record various intermolecular interactions, indicating the stabilization of the AMA structure by the intermolecular weak C-H center dot center dot center dot O hydrogen bonds and pi center dot center dot center dot pi interactions. The title compound was screened for antibacterial and antifungal activities using a serial dilution technique under aseptic conditions. The results indicate that the title compound has significant antibacterial properties but showed no antifungal behavior.eninfo:eu-repo/semantics/openAccessCarboxylic-Acid AnhydridesIntermolecular InteractionsAldehydesVisualizationEstersCdcDftArticle720171921720110.1021/acsomega.2c00879356474482-s2.0-85131147650Q1WOS:000820291200001Q2