Yokus, Ozlem AktasKardas, FarukAkyildirim, OnurEren, TanjuAtar, NecipYola, Mehmet Lutfi2025-03-232025-03-2320160925-4005https://doi.org/10.1016/j.snb.2016.04.050https://hdl.handle.net/11486/6035In this report, a novel voltammetric sensor based on polyoxometalate (H3PW12040, POM) functionalized reduced graphene oxide (rGO) modified glassy carbon electrode (GCE) was presented for simultaneous determination of L-tyrosine (L-Tyr) and L-tryptophan (L-Trp). The nanocomposites were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The electrochemical determination of L-Tyr and L-Trp has been studied using square wave voltammetry (SWV) on GCE modified with POM-rGO composite (POM-rGOIGCE). The developed method was also applied successfully for the simultaneous determination of L-Tyr and L-Trp in spiked serum sample and the linearity range of L-Tyr and L-Trp was 1.0 x 10(-11) - 1.0 x 10(-9)M with the detection limit of 2.0 x 10(-12)M. (C) 2016 Elsevier B.V. All rights reserved.eninfo:eu-repo/semantics/closedAccessL-TyrosineL-TryptophanReduced graphene oxidePolyoxometalateSensorArticle233475410.1016/j.snb.2016.04.0502-s2.0-84963717653Q1WOS:000376384100007Q1